Qin An

Qin An

Computational biologist

Publications

You can also find my articles on my Google Scholar profile.

Journal articles

  1. An Q, Hu Y, Li Q, Chen X, Huang J, Pellegrini M, Zhou X, Rettig M, Fan G. The size of cell free mitochondrial DNA in blood is inversely correlated with tumor burden in cancer patients. Precision Clinical Medicine 2 (3), 131-139 (first author).
  2. Lv B‡, An Q‡, Zeng Q‡, Lu P, Zhu X, Ji Y, Fan G, Xue Z. Single-Cell RNA Sequencing Reveals Regulatory Mechanism for Trophoblast Cell-Fate Divergence in Human Peri-Implantation Embryo. PLoS biology 17 (10), e3000187 (‡co-first author).
  3. Mao X‡, An Q‡, Xi H, Yuan S, Yang X, Wang J, Hu Y, Liu Q, Fan G. Single cell RNA sequencing of hESC-derived 3D retinal organoids reveals novel genes regulating RPC commitment in early human retinogenesis. Stem cell reports 13 (4), 747-760 (‡co-first author).
  4. Hu Y‡, An Q‡, Guo Y‡, Zhong J, Fan S, Rao P, Liu X, Liu Y, Fan G. Simultaneous Profiling of mRNA Transcriptome and DNA Methylome from a Single Cell. Single Cell Methods 2019 (pp. 363-377). Humana, New York, NY. (‡co-first author, book chapter)
  5. Hu Y‡, An Q‡, Fan G#. Single cell multi-omics analysis reveals novel roles for DNA methylation in sensory neuron injury responses. (‡co-first author, preprint on Biorxiv)
  6. Hu Y, Huang K, An Q, Du G, Hu G, Xue J, Zhu X, Wang C, Xue Z, Fan, G. Simultaneous profiling of transcriptome and DNA methylome from a single cell[J]. Genome biology, 2016, 17(1): 88.
  7. Song Q, Yuan S, An Q, et al. Directed differentiation of human embryonic stem cells to corneal endothelial cell-like cells: a transcriptomic analysis[J]. Experimental eye research, 2016, 151: 107-114.
  8. Hu Y, An Q, Sheu K, Trejo B, Fan S, Guo Y. Single cell multi-omics technology: methodology and application[J]. Frontiers in cell and developmental biology, 2018, 6.
  9. Hu Y, Zhong J, Xiao Y, Xing Z, Sheu K, Fan S, An Q, Rap P, Qiu Y, Zheng Y, Liu X, Fan G, Liu Y. (2020). Single-cell RNA cap and tail sequencing (scRCAT-seq) reveals subtype-specific isoforms differing in transcript demarcation. Nature communications, 11(1), 5148.
  10. Guo S, Zhang D, Wang H, An Q, Yu G, Han J, Jiang C, & Huang J. (2023). Computational and systematic analysis of multi-omics data for drug discovery and development. Frontiers in Medicine, 10, 1146896.
  11. Ding X, An Q, Zhao W, et al. Distinct patterns of responses in endothelial cells and smooth muscle cells following vascular injury[J]. JCI insight, 2022, 7(20).
  12. Jansova D, Aleshkina D, Jindrova A, Iyyappan R, An Q, Fan G, & Susor A. (2021). Single molecule RNA localization and translation in the mammalian oocyte and embryo. Journal of Molecular Biology, 433(19), 167166.
  13. Song Y, Soto J, Wang P, An Q, Zhang X, Hong S, … & Li, S. (2021). Asymmetric cell division of fibroblasts is an early deterministic step to generate elite cells during cell reprogramming. Advanced Science, 8(7), 2003516.
  14. Hu Y, Huang K, Zeng Q, Feng Y, Ke Q, An Q, … & Fan, G. (2021). Single‐cell analysis of nonhuman primate preimplantation development in comparison to humans and mice. Developmental Dynamics, 250(7), 974-985.
  15. Zeng Q, Feng Y, Hu Y, An Q, Li T, Qin L, Xue Z, Huang K, Liu J, Fan G. X-chromosome dosage compensation dynamics in human early embryos (preprint on BioRxiv).

Conference presentations

  1. CRP-R2: Genomic Analysis of Stem Cell Differentiation in Human Overgrowth Syndrome. 2018 Fourth Annual Stem Cell Genomics CIRM Retreat, May 17-18, 2018. Sanford Consortium for Regenerative Medicine, Roth Auditorium, San Diego. (Oral presentation)

  2. ID 633108: Single cell RNA sequencing of hESC-derived 3D retinal organoids reveals novel genes regulating progenitor commitment in early human retinogenesis. International Society for Stem Cell Research (ISSCR) 2019 Annual Meeting, June 26-29, 2019. Los Angeles Convention Center, Los Angeles. (Poster presentation)